Gene Information
Gene NameGNLY
OrganismHomo sapiens (Human)
Gene Length145
Protein NamesGranulysin (Lymphokine LAG-2) (Protein NKG5) (T-cell activation protein 519)
Target Namegranulysin
Target TypeNA
Gene Age454 ( ENSG00000115523 )
Evolutionary StageMammalia
AlphaFoldDBP22749
Gene CardGNLY
Uniprot IDP22749
PfamNA
In ASDno
Allosteric Predictionno (-0.769066397)
Ortholog in AnimalsAlpaca_ GNLY ( ortholog_one2one )
Pig_ GNLY ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuespleen, whole.blood
Tissue SpecificityExpressed in natural killer and T-cells.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1L9L  (X-ray  0.92A 
DBSNP rs11127 
Subcellular location [CC]Secreted. Note=Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.
Mouse PG classificationNA
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