| Gene Information | |
|---|---|
| Gene Name | ATP9A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1047 |
| Protein Names | Probable phospholipid-transporting ATPase IIA (EC 7.6.2.1) (ATPase class II type 9A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000054793 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75110 |
| Gene Card | ATP9A |
| Uniprot ID | O75110 |
| Pfam | PF16212; PF16209 |
| In ASD | no |
| Allosteric Prediction | no (-0.963248035) |
| Ortholog in Animals | Alpaca_ ATP9A ( ortholog_one2one ) Dog_ ATP9A ( ortholog_one2one ) GuineaPig_ ATP9A ( ortholog_one2one ) Macaque_ ATP9A ( ortholog_one2one ) Mouse_ Atp9a ( ortholog_one2one ) Pig_ ATP9A ( ortholog_one2one ) Rat_ Atp9a ( ortholog_one2one ) Rabbit_ ATP9A ( ortholog_one2one ) |
| Ohnologs | ATP9B |
| Paralogs | ATP8B4, ATP10D, ATP11A, ATP8A2, ATP11C, ATP10A, ATP11B, ATP8B1, ATP10B, ATP8B2, ATP8A1, ATP9B, ATP8B3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome membrane {ECO:0000269|PubMed:21914794, ECO:0000269|PubMed:27733620, ECO:0000269|PubMed:30213940}; Multi-pass membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000269|PubMed:21914794, ECO:0000269|PubMed:27733620}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:21914794, ECO:0000269|PubMed:27733620, ECO:0000269|PubMed:30213940}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:30947313}; Multi-pass membrane protein. Note=Efficient exit from the endoplasmic reticulum does not require TMEM30A, nor TMEM30B (PubMed:21914794). Transiently expressed in the plasma membrane (PubMed:30947313). {ECO:0000269|PubMed:21914794, ECO:0000269|PubMed:30947313}. |
| Mouse PG classification | NA |
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