| Gene Information | |
|---|---|
| Gene Name | GNL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 731 |
| Protein Names | Nucleolar GTP-binding protein 2 (Autoantigen NGP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000134697 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q13823 |
| Gene Card | GNL2 |
| Uniprot ID | Q13823 |
| Pfam | PF01926; PF08153 |
| In ASD | no |
| Allosteric Prediction | no (-1.001691596) |
| Ortholog in Animals | Alpaca_ GNL2 ( ortholog_one2one ) Dog_ GNL2 ( ortholog_one2one ) GuineaPig_ GNL2 ( ortholog_one2one ) Macaque_ GNL2 ( ortholog_one2one ) Mouse_ Gnl2 ( ortholog_one2one ) Pig_ GNL2 ( ortholog_one2one ) Rat_ Gnl2 ( ortholog_one2one ) Rabbit_ GNL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NOA1, LSG1, GNL1, MTG1, GNL3, GNL3L |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with the highest expression level in testis. {ECO:0000269|PubMed:8822211}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.014345(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6LSS (EM 3.23A ) 6LU8 (EM 3.13A ) |
| DBSNP | rs12025870 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:21495629}. |
| Mouse PG classification | NA |
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