| Gene Information | |
|---|---|
| Gene Name | GNG8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 69 |
| Protein Names | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 (G gamma-C) (G-gamma-8) (G-gamma-9) (Guanine nucleotide binding protein gamma transducing activity polypeptide 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000167414 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14610 |
| Gene Card | GNGT2 |
| Uniprot ID | O14610 |
| Pfam | PF00631 |
| In ASD | no |
| Allosteric Prediction | yes (0.26847905) |
| Ortholog in Animals | Alpaca_ GNG8 ( ortholog_one2one ) Dog_ GNG8 ( ortholog_one2one ) GuineaPig_ GNG8 ( ortholog_one2one ) Mouse_ Gng8 ( ortholog_one2one ) Pig_ GNG8 ( ortholog_one2one ) Rat_ Gng8 ( ortholog_one2one ) Rabbit_ GNG8 ( ortholog_one2one ) |
| Ohnologs | GNG3, GNG2 |
| Paralogs | GNG11, GNG5, GNGT1, GNG5P2, GNGT2, GNG10, GNG2, GNG4, GNG3, GNG12, GNG7 |
| Tissue | NA |
| Tissue Specificity | Retinal cones. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.12(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9895097 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Mouse PG classification | NA |
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