| Gene Information | |
|---|---|
| Gene Name | GNG4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 75 |
| Protein Names | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000168243 ) 3 ( ENSG00000282972 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P50150 |
| Gene Card | GNG4 |
| Uniprot ID | P50150 |
| Pfam | PF00631 |
| In ASD | no |
| Allosteric Prediction | yes (0.18995236) |
| Ortholog in Animals | Alpaca_ GNG4 ( ortholog_one2one ) Dog_ GNG4 ( ortholog_one2one ) GuineaPig_ GNG4 ( ortholog_one2one ) Macaque_ GNG4 ( ortholog_one2one ) Mouse_ Gng4 ( ortholog_one2one ) Pig_ GNG4 ( ortholog_one2one ) Rat_ Gng4 ( ortholog_one2one ) |
| Ohnologs | GNG3, GNG2 |
| Paralogs | GNG11, GNG5, GNGT1, GNG5P2, GNGT2, GNG10, GNG3, GNG2, GNG8, GNG12, GNG7 |
| Tissue | adrenal.gland, cerebral.cortex, ovary, prostate, brain |
| Tissue Specificity | Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.08(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Mouse PG classification | NA |
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