| Gene Information | |
|---|---|
| Gene Name | GNB5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 395 |
| Protein Names | Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000069966 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14775 |
| Gene Card | GNB5 |
| Uniprot ID | O14775 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | yes (1.615583804) |
| Ortholog in Animals | Alpaca_ GNB5 ( ortholog_one2one ) Dog_ GNB5 ( ortholog_one2one ) GuineaPig_ GNB5 ( ortholog_one2one ) Macaque_ GNB5 ( ortholog_one2one ) Mouse_ Gnb5 ( ortholog_one2one ) Pig_ GNB5 ( ortholog_one2one ) Rat_ Gnb5 ( ortholog_one2one ) Rabbit_ GNB5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GNB3, GNB4, GNB2, GNB1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:9606987}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.020460(Rat);0.059259(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7EWP (EM 4.30A ) 7EWR (EM 4.70A ) |
| DBSNP | rs761399728 rs34637551 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:P62881}. |
| Mouse PG classification | NA |
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