| Gene Information | |
|---|---|
| Gene Name | GNB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 340 |
| Protein Names | Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000114450 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9HAV0 |
| Gene Card | GNB4 |
| Uniprot ID | Q9HAV0 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | yes (1.504092722) |
| Ortholog in Animals | Alpaca_ GNB4 ( ortholog_one2one ) Dog_ GNB4 ( ortholog_one2one ) GuineaPig_ GNB4 ( ortholog_one2one ) Macaque_ GNB4 ( ortholog_one2one ) Mouse_ Gnb4 ( ortholog_one2one ) Pig_ GNB4 ( ortholog_one2one ) Rat_ Gnb4 ( ortholog_one2one ) Rabbit_ GNB4 ( ortholog_one2one ) |
| Ohnologs | GNB3, GNB2, GNB1 |
| Paralogs | GNB2, GNB3, GNB1, GNB5 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart. Abundantly expressed in the axons and Schwann cells of peripheral nerves. {ECO:0000269|PubMed:11842130, ECO:0000269|PubMed:23434117}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.213488(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs387907340 rs387907341 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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