| Gene Information | |
|---|---|
| Gene Name | CHODL |
| Organism | Homo sapiens (Human) |
| Gene Length | 273 |
| Protein Names | Chondrolectin (Transmembrane protein MT75) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000154645 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H9P2 |
| Gene Card | CHODL |
| Uniprot ID | Q9H9P2 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | no (-1.534123413) |
| Ortholog in Animals | Alpaca_ CHODL ( ortholog_one2one ) Dog_ CHODL ( ortholog_one2one ) GuineaPig_ CHODL ( ortholog_one2one ) Macaque_ CHODL ( ortholog_one2one ) Mouse_ Chodl ( ortholog_one2one ) Pig_ CHODL ( ortholog_one2one ) Rat_ Chodl ( ortholog_one2one ) |
| Ohnologs | LAYN |
| Paralogs | LAYN |
| Tissue | testis |
| Tissue Specificity | Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. B lymphocytes express isoform 2 only; peripheral blood T lymphocytes express isoform 3 only; granulocytes and monocytes express neither isoform 2 nor isoform 3. During development of T lymphocytes, bone marrow progenitor cells express isoform 2 only; thymocytes at different stages of maturation express predominantly isoform 2 and weakly isoform 3, and mature thymocytes express only isoform 2. {ECO:0000269|PubMed:11707072, ECO:0000269|PubMed:12079284, ECO:0000269|PubMed:12621022}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22042635}. Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 2]: Endoplasmic reticulum {ECO:0000269|PubMed:12621022}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 3]: Cytoplasm {ECO:0000269|PubMed:12621022}. |
| Mouse PG classification | NA |
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