| Gene Information | |
|---|---|
| Gene Name | GNAS |
| Organism | Homo sapiens (Human) |
| Gene Length | 245 |
| Protein Names | Neuroendocrine secretory protein 55 (NESP55) [Cleaved into: LHAL tetrapeptide; GPIPIRRH peptide] |
| Target Name | guanine nucleotide-binding protein g(s) subunit alpha isoforms short |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000087460 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O95467 |
| Gene Card | GNAS |
| Uniprot ID | O95467 |
| Pfam | PF06390 |
| In ASD | no |
| Allosteric Prediction | yes (1.631221858) |
| Ortholog in Animals | Alpaca_ GNAS ( ortholog_one2one ) Dog_ GNAS ( ortholog_one2one ) GuineaPig_ GNAS ( ortholog_one2one ) Macaque_ GNAS ( ortholog_one2one ) Mouse_ Gnas ( ortholog_one2one ) Rat_ Gnas ( ortholog_one2one ) |
| Ohnologs | GNAL |
| Paralogs | GNAZ, GNAT1, GNAL, GNA13, GNA12, GNAI2, GNAT2, GNAO1, GNAI3, GNAI1, GNA15, GNA11, GNAT3, GNA14, GNAQ |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Secreted {ECO:0000250}. Note=Neuroendocrine secretory granules. {ECO:0000250}. |
| Mouse PG classification | NA |
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