| Gene Information | |
|---|---|
| Gene Name | RGMB |
| Organism | Homo sapiens (Human) |
| Gene Length | 437 |
| Protein Names | Repulsive guidance molecule B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000174136 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6NW40 |
| Gene Card | RGMB |
| Uniprot ID | Q6NW40 |
| Pfam | PF06534; PF06535 |
| In ASD | no |
| Allosteric Prediction | no (-0.899539074) |
| Ortholog in Animals | Alpaca_ RGMB ( ortholog_one2one ) Dog_ RGMB ( ortholog_one2one ) GuineaPig_ RGMB ( ortholog_one2one ) Macaque_ RGMB ( ortholog_one2one ) Mouse_ Rgmb ( ortholog_one2one ) Pig_ RGMB ( ortholog_one2one ) Rat_ Rgmb ( ortholog_one2one ) Rabbit_ RGMB ( ortholog_one2one ) |
| Ohnologs | RGMA, HJV |
| Paralogs | HJV, RGMA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4BQ6 (X-ray 2.30A ) 4BQ7 (X-ray 6.60A ) 4BQ8 (X-ray 2.80A ) 4UHZ (X-ray 2.85A ) 4UI0 (X-ray 2.80A ) 4UI2 (X-ray 3.15A ) 6Z3H (X-ray 3.16A ) 6Z3J (X-ray 1.65A ) 6Z3M (X-ray 5.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q7TQ33}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q7TQ33}. Membrane raft {ECO:0000250|UniProtKB:Q7TQ33}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |