Gene Information
Gene NameGNAL
OrganismHomo sapiens (Human)
Gene Length381
Protein NamesGuanine nucleotide-binding protein G(olf) subunit alpha (Adenylate cyclase-stimulating G alpha protein, olfactory type)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000141404 )
Evolutionary StageEumetazoa
AlphaFoldDBP38405
Gene CardGNAL
Uniprot IDP38405
PfamPF00503
In ASDno
Allosteric Predictionno (-0.060735743)
Ortholog in AnimalsAlpaca_ GNAL ( ortholog_one2one )
Dog_ GNAL ( ortholog_one2one )
GuineaPig_ GNAL ( ortholog_one2one )
Macaque_ GNAL ( ortholog_one2one )
Mouse_ Gnal ( ortholog_one2one )
Pig_ GNAL ( ortholog_one2one )
Rat_ Gnal ( ortholog_one2one )
Rabbit_ GNAL ( ortholog_one2one )
OhnologsGNAS
ParalogsGNAZ, GNAT1, GNA13, GNA12, GNAI2, GNAT2, GNAO1, GNAI3, GNAI1, GNA15, GNA11, GNAT3, GNAS, GNA14, GNAQ
Tissueputamen
Tissue SpecificityDetected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
Pharmacological Animal ModelsNULL(Chimpanzee);0.149194(Mouse);0.001823(Rat);0.040000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1039372506  rs398122923  rs398122925 
Subcellular location [CC]NA
Mouse PG classificationHPG
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