| Gene Information | |
|---|---|
| Gene Name | GNAI2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 355 |
| Protein Names | Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P04899 |
| Gene Card | GNAI2 |
| Uniprot ID | P04899 |
| Pfam | PF00503 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.230413(Chimpanzee);0.191999(Mouse);0.001546(Rat);0.036842(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6D9H (EM 3.60A ) 7F8V (EM 3.30A ) 7LD3 (EM 3.20A ) 7LD4 (EM 3.30A ) 7WV9 (EM 3.36A ) 7WVV (EM 2.90A ) 7WVW (EM 3.10A ) 7WVX (EM 2.80A ) 7WVY (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17635935}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17635935}. Cell membrane {ECO:0000269|PubMed:17635935}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. |
| Mouse PG classification | NA |
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