| Gene Information | |
|---|---|
| Gene Name | GNA11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000088256 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P29992 |
| Gene Card | GNA11 |
| Uniprot ID | P29992 |
| Pfam | PF00503 |
| In ASD | no |
| Allosteric Prediction | yes (1.334239435) |
| Ortholog in Animals | Alpaca_ GNA11 ( ortholog_one2one ) Dog_ GNA11 ( ortholog_one2one ) GuineaPig_ GNA11 ( ortholog_one2one ) Macaque_ GNA11 ( ortholog_one2one ) Mouse_ Gna11 ( ortholog_one2one ) Pig_ GNA11 ( ortholog_one2one ) Rat_ Gna11 ( ortholog_one2one ) |
| Ohnologs | GNA14, GNAQ |
| Paralogs | GNAZ, GNAT1, GNAL, GNA13, GNA12, GNAI2, GNAT2, GNAO1, GNAI3, GNAI1, GNA15, GNAT3, GNAS, GNA14, GNAQ |
| Tissue | NA |
| Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:18703424}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.002240(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6OIJ (EM 3.30A ) 7RKF (EM 4.00A ) |
| DBSNP | rs587777021 rs587777019 rs587777020 rs672601249 rs587777022 rs140749796 |
| Subcellular location [CC] | Cell membrane {ECO:0000305|PubMed:18703424}; Lipid-anchor {ECO:0000305|PubMed:18703424}. Cytoplasm {ECO:0000269|PubMed:18703424}. Note=In testicular cells, expressed exclusively in the cytoplasm. {ECO:0000269|PubMed:18703424}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |