| Gene Information | |
|---|---|
| Gene Name | HAGH |
| Organism | Homo sapiens (Human) |
| Gene Length | 308 |
| Protein Names | Hydroxyacylglutathione hydrolase, mitochondrial (EC 3.1.2.6) (Glyoxalase II) (Glx II) |
| Target Name | hydroxyacylglutathione hydrolase, mitochondrial |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000063854 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q16775 |
| Gene Card | HAGH |
| Uniprot ID | Q16775 |
| Pfam | PF16123; PF00753 |
| In ASD | no |
| Allosteric Prediction | yes (0.117886601) |
| Ortholog in Animals | Alpaca_ HAGH ( ortholog_one2one ) Dog_ HAGH ( ortholog_one2one ) GuineaPig_ HAGH ( ortholog_one2one ) Macaque_ HAGH ( ortholog_one2one ) Mouse_ Hagh ( ortholog_one2one ) Rat_ Hagh ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PNKD, ETHE1, MBLAC2, HAGHL |
| Tissue | NA |
| Tissue Specificity | Expressed in liver and kidney. {ECO:0000269|PubMed:15117945}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1QH3 (X-ray 1.90A ) 1QH5 (X-ray 1.45A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Mitochondrion matrix {ECO:0000269|PubMed:15117945}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:15117945}. |
| Mouse PG classification | NA |
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