| Gene Information | |
|---|---|
| Gene Name | GMPR |
| Organism | Homo sapiens (Human) |
| Gene Length | 345 |
| Protein Names | GMP reductase 1 (GMPR 1) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1) |
| Target Name | gmp reductase 1 |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000137198 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P36959 |
| Gene Card | GMPR |
| Uniprot ID | P36959 |
| Pfam | PF00478 |
| In ASD | no |
| Allosteric Prediction | yes (0.15593122) |
| Ortholog in Animals | Alpaca_ GMPR ( ortholog_one2one ) Dog_ GMPR ( ortholog_one2one ) GuineaPig_ GMPR ( ortholog_one2one ) Macaque_ GMPR ( ortholog_one2one ) Mouse_ Gmpr ( ortholog_one2one ) Pig_ GMPR ( ortholog_one2one ) Rat_ Gmpr ( ortholog_one2one ) Rabbit_ GMPR ( ortholog_one2one ) |
| Ohnologs | GMPR2 |
| Paralogs | IMPDH1, IMPDH2, GMPR2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BLE (X-ray 1.90A ) 2BWG (X-ray 2.40A ) |
| DBSNP | rs760571328 rs1042391 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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