Gene Information
Gene NameTKTL2
OrganismHomo sapiens (Human)
Gene Length626
Protein NamesTransketolase-like protein 2 (EC 2.2.1.1)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000151005 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9H0I9
Gene CardTKTL2
Uniprot IDQ9H0I9
PfamPF02779; PF02780; PF00456
In ASDno
Allosteric Predictionno (-0.436896972)
Ortholog in AnimalsAlpaca_ TKTL2 ( ortholog_one2one )
GuineaPig_ TKTL2 ( ortholog_one2one )
Macaque_ TKTL2 ( ortholog_one2one )
Mouse_ Tktl2 ( ortholog_one2one )
Pig_ TKTL2 ( ortholog_one2one )
Rat_ Tktl2 ( ortholog_one2one )
Rabbit_ TKTL2 ( ortholog_one2one )
OhnologsTKTL1, TKT
ParalogsBCKDHB, PDHB, TKTL1, TKT
Tissuetestis
Tissue SpecificityOverexpressed in hepatoma cancer cells. {ECO:0000269|PubMed:17321041}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.065833(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3811750  rs11735477 
Subcellular location [CC]NA
Mouse PG classificationNA
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