| Gene Information | |
|---|---|
| Gene Name | CSF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | Granulocyte colony-stimulating factor (G-CSF) (Pluripoietin) (Filgrastim) (Lenograstim) |
| Target Name | granulocyte colony-stimulating factor |
| Target Type | Successful target |
| Gene Age | 645 ( ENSG00000108342 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P09919 |
| Gene Card | CSF3 |
| Uniprot ID | P09919 |
| Pfam | PF16647 |
| In ASD | no |
| Allosteric Prediction | yes (0.515038381) |
| Ortholog in Animals | Alpaca_ CSF3 ( ortholog_one2one ) Dog_ CSF3 ( ortholog_one2one ) GuineaPig_ CSF3 ( ortholog_one2one ) Macaque_ CSF3 ( ortholog_one2one ) Mouse_ Csf3 ( ortholog_one2one ) Pig_ CSF3 ( ortholog_one2one ) Rat_ Csf3 ( ortholog_one2one ) Rabbit_ CSF3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | appendix, esophagus, urinary.bladder |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CD9 (X-ray 2.80A ) 1GNC (NMR - ) 1PGR (X-ray 3.50A ) 1RHG (X-ray 2.20A ) 2D9Q (X-ray 2.80A ) 5GW9 (X-ray 1.65A ) 5ZO6 (X-ray 1.70A ) |
| DBSNP | rs2227329 rs2227330 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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