| Gene Information | |
|---|---|
| Gene Name | INSL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 139 |
| Protein Names | Early placenta insulin-like peptide (EPIL) (Insulin-like peptide 4) (Placentin) [Cleaved into: Early placenta insulin-like peptide B chain; Early placenta insulin-like peptide A chain] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000120211 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q14641 |
| Gene Card | INSL4 |
| Uniprot ID | Q14641 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.129584271) |
| Ortholog in Animals | Alpaca_ INSL4 ( ortholog_one2one ) Dog_ RLN2 ( ortholog_one2many ) Macaque_ INSL4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RLN2, RLN1, INSL6 |
| Tissue | placenta |
| Tissue Specificity | Expressed in placenta, uterus and in fetal perichondrium. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells. {ECO:0000269|PubMed:12414911, ECO:0000269|PubMed:9740319}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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