Gene Information
Gene NameGLUR2
OrganismHomo sapiens (Human)
Gene Length883
Protein NamesGlutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP42262
Gene CardGRIA2
Uniprot IDP42262
PfamPF01094; PF00060; PF10613
In ASDyes
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.357195(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2WJW  (X-ray  1.80A  )  2WJX  (X-ray  4.10A  )  2XHD  (X-ray  1.80A  )  3R7X  (X-ray  2.10A  )  3RN8  (X-ray  1.70A  )  3RNN  (X-ray  1.75A  )  3UA8  (X-ray  1.90A  )  5H8S  (X-ray  1.70A  )  5YBF  (X-ray  1.50A  )  5YBG  (X-ray  1.52A  )  5ZG0  (X-ray  1.58A  )  5ZG1  (X-ray  1.32A  )  5ZG2  (X-ray  1.25A  )  5ZG3  (X-ray  1.65A  )  7F3O  (X-ray  1.44A  ) 
DBSNP rs1735116193  rs1735294501  rs17850674  rs17850675  rs1735303754  rs1553956958  rs1579377564 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:23739980, ECO:0000269|PubMed:31300657};
Multi-pass membrane protein {ECO:0000269|PubMed:23739980}. Endoplasmic reticulum membrane {ECO:0000250};
Multi-pass membrane protein {ECO:0000250}. Postsynaptic cell membrane {ECO:0000269|PubMed:23739980};
Multi-pass membrane protein {ECO:0000269|PubMed:23739980}. Postsynaptic density membrane {ECO:0000250|UniProtKB:P23819};
Multi-pass membrane protein {ECO:0000250|UniProtKB:P23819}. Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression (By similarity). Displays a somatodendritic localization and is excluded from axons in neurons (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:P23819}.
Mouse PG classificationNA
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