| Gene Information | |
|---|---|
| Gene Name | GLUP |
| Organism | Homo sapiens (Human) |
| Gene Length | 296 |
| Protein Names | Parkin coregulated gene protein (Molecular chaperone/chaperonin-binding protein) (PARK2 coregulated gene protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96M98 |
| Gene Card | PACRG |
| Uniprot ID | Q96M98 |
| Pfam | PF10274 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all immune tissues, spleen, lymph nodes, thymus, tonsils, leukocyte and bone marrow. Expressed also in heart, brain, skeletal muscle, kidney, lung and pancreas. Expressed in primary Schwann cells and very weakly by monocyte-derived macrophages the primary host cells of Mycobacterium leprae, the causative agent of leprosy. Component of Lewy bodies, intraneuronal inclusions found in the brain of Parkinson disease patients. {ECO:0000269|PubMed:14737177}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6NDU (X-ray 2.10A ) 6NEP (X-ray 2.10A ) 6UCC (X-ray 2.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A5PK71}. |
| Mouse PG classification | NA |
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