| Gene Information | |
|---|---|
| Gene Name | APOL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | Apolipoprotein L4 (Apolipoprotein L-IV) (ApoL-IV) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000100336 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9BPW4 |
| Gene Card | APOL4 |
| Uniprot ID | Q9BPW4 |
| Pfam | PF05461 |
| In ASD | no |
| Allosteric Prediction | no (-1.273792333) |
| Ortholog in Animals | Macaque_ APOL4 ( ortholog_one2one ) Mouse_ Apol7a ( ortholog_many2many ) Mouse_ Apol7c ( ortholog_many2many ) Mouse_ Apol11a ( ortholog_many2many ) Mouse_ Apol8 ( ortholog_many2many ) Mouse_ Apol7e ( ortholog_many2many ) Mouse_ Apol7b ( ortholog_many2many ) Mouse_ Apol11b ( ortholog_many2many ) Mouse_ Apol10a ( ortholog_many2many ) Mouse_ Apol9a ( ortholog_many2many ) Mouse_ Apol9b ( ortholog_many2many ) Mouse_ Apol10b ( ortholog_many2many ) Rat_ Apol3 ( ortholog_many2many ) Rat_ AABR07058464.1 ( ortholog_many2many ) Rat_ AABR07058479.1 ( ortholog_many2many ) Rat_ Apol2 ( ortholog_many2many ) Rat_ RGD1309808 ( ortholog_many2many ) Rat_ Apol9a ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | APOL3, APOL1, APOL2, APOL6, APOL5, APOLD1 |
| Tissue | adipose.tissue, lung |
| Tissue Specificity | Widely expressed; the highest levels are in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis; levels are low in brain, heart and pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs132736 rs80587 rs132700 rs2227168 rs6000173 rs6000172 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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