Gene Information
Gene NameGLNS
OrganismHomo sapiens (Human)
Gene Length373
Protein NamesGlutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL) (EC 2.3.1.225)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP15104
Gene CardGLUL
Uniprot IDP15104
PfamPF00120; PF03951
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in endothelial cells. {ECO:0000269|PubMed:30158707}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2OJW  (X-ray  2.05A  2QC8  (X-ray  2.60A  7EVT  (X-ray  2.95A 
DBSNP rs80358214  rs80358215 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:30158707}. Microsome {ECO:0000250|UniProtKB:P09606}. Mitochondrion {ECO:0000250|UniProtKB:P09606}. Cell membrane {ECO:0000269|PubMed:30158707};
Lipid-anchor {ECO:0000269|PubMed:30158707}. Note=Mainly localizes in the cytosol, with a fraction associated with the cell membrane. {ECO:0000269|PubMed:30158707}.
Mouse PG classificationNA
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