| Gene Information | |
|---|---|
| Gene Name | GLIS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 775 |
| Protein Names | Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000107249 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NEA6 |
| Gene Card | GLIS3 |
| Uniprot ID | Q8NEA6 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.353306266) |
| Ortholog in Animals | Alpaca_ GLIS3 ( ortholog_one2one ) Dog_ GLIS3 ( ortholog_one2one ) GuineaPig_ GLIS3 ( ortholog_one2one ) Macaque_ GLIS3 ( ortholog_one2one ) Mouse_ Glis3 ( ortholog_one2one ) Pig_ GLIS3 ( ortholog_one2one ) Rat_ Glis3 ( ortholog_one2one ) Rabbit_ GLIS3 ( ortholog_one2one ) |
| Ohnologs | GLI1 |
| Paralogs | AEBP2, GLI2, ZXDC, GLIS2, GLIS1, ZXDA, ZXDB, ZIC4, ZIC5, ZIC3, ZIC2, GLI1, GLI3, ZIC1 |
| Tissue | thyroid |
| Tissue Specificity | In the adult, expressed at high levels in the kidney and at lower levels in the brain, skeletal muscle, pancreas, liver, lung, thymus and ovary. {ECO:0000269|PubMed:14500813}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs806052 rs6415788 rs10973986 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | HPG |
| click here to return to the previous page | |