| Gene Information | |
|---|---|
| Gene Name | GLIS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 524 |
| Protein Names | Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000126603 ) 3 ( ENSG00000274636 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BZE0 |
| Gene Card | GLIS2 |
| Uniprot ID | Q9BZE0 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-1.763217967) |
| Ortholog in Animals | Alpaca_ GLIS2 ( ortholog_one2one ) Dog_ GLIS2 ( ortholog_one2one ) GuineaPig_ GLIS2 ( ortholog_one2one ) Macaque_ GLIS2 ( ortholog_one2one ) Mouse_ Glis2 ( ortholog_one2one ) Pig_ GLIS2 ( ortholog_one2one ) Rat_ Glis2 ( ortholog_one2one ) Rabbit_ GLIS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AEBP2, GLIS3, GLI2, ZXDC, GLIS1, ZXDA, ZXDB, ZIC4, ZIC5, ZIC3, ZIC2, GLI1, GLI3, ZIC1 |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in kidney and at low levels in heart, lung and placenta. Expressed in colon. {ECO:0000269|PubMed:11738817, ECO:0000269|PubMed:17289029}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8057701 |
| Subcellular location [CC] | Nucleus speckle {ECO:0000250}. Cytoplasm {ECO:0000250}. |
| Mouse PG classification | HPG |
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