| Gene Information | |
|---|---|
| Gene Name | STT3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 826 |
| Protein Names | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000163527 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q8TCJ2 |
| Gene Card | STT3B |
| Uniprot ID | Q8TCJ2 |
| Pfam | PF02516 |
| In ASD | no |
| Allosteric Prediction | no (-1.200486324) |
| Ortholog in Animals | Alpaca_ STT3B ( ortholog_one2one ) Dog_ STT3B ( ortholog_one2one ) GuineaPig_ STT3B ( ortholog_one2one ) Macaque_ STT3B ( ortholog_one2one ) Mouse_ Stt3b ( ortholog_one2one ) Pig_ STT3B ( ortholog_one2one ) Rat_ Stt3b ( ortholog_one2one ) Rabbit_ STT3B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RPL35, STT3A |
| Tissue | testis |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, muscle, kidney and pancreas. Expressed in skin fibroblasts (at protein level). {ECO:0000269|PubMed:12887896}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.051850(Rat);0.257804(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 6S7T (EM 3.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:12887896}. Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P39007}. |
| Mouse PG classification | NA |
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