| Gene Information | |
|---|---|
| Gene Name | GLIPR1L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 242 |
| Protein Names | GLIPR1-like protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000173401 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q6UWM5 |
| Gene Card | GLIPR1L1 |
| Uniprot ID | Q6UWM5 |
| Pfam | PF00188 |
| In ASD | no |
| Allosteric Prediction | no (-1.476616205) |
| Ortholog in Animals | Alpaca_ GLIPR1L1 ( ortholog_one2one ) Dog_ GLIPR1L1 ( ortholog_one2one ) GuineaPig_ GLIPR1L1 ( ortholog_one2one ) Macaque_ GLIPR1L1 ( ortholog_one2one ) Mouse_ Glipr1l3 ( ortholog_one2many ) Mouse_ Glipr1l1 ( ortholog_one2many ) Pig_ GLIPR1L1 ( ortholog_one2one ) Rat_ Glipr1l1 ( ortholog_one2one ) |
| Ohnologs | CRISP2 |
| Paralogs | CRISP2, GLIPR1, CLEC18C, CLEC18A, CLEC18B, R3HDML, CRISPLD1, CRISP1, GLIPR2, PI15, GLIPR1L2, CRISPLD2, CRISP3 |
| Tissue | testis |
| Tissue Specificity | Highly expressed in testis. {ECO:0000269|PubMed:16714093}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9DAG6}. Cell membrane {ECO:0000250|UniProtKB:Q9DAG6}; Lipid-anchor, GPI-anchor {ECO:0000255}; Extracellular side {ECO:0000250|UniProtKB:Q9DAG6}. Membrane raft {ECO:0000250|UniProtKB:Q32LB5}. Secreted {ECO:0000250|UniProtKB:Q9DAG6}. Note=Located in the connecting piece of elongated spermatids and sperm. Also located in the apical region of the sperm head after sperm capacitation (By similarity). Weakly attached to the cell membrane and later secreted into the extracellular space (By similarity). Located on sperm equatorial segment and neck (By similarity). Associated with epididymosomes from the caput and cauda epididymis (By similarity). {ECO:0000250|UniProtKB:Q32LB5, ECO:0000250|UniProtKB:Q9DAG6}. |
| Mouse PG classification | NA |
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