Gene Information
Gene NameGLEPP1
OrganismHomo sapiens (Human)
Gene Length1216
Protein NamesReceptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ16827
Gene CardPTPRO
Uniprot IDQ16827
PfamPF00041; PF00102
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityGlomerulus of kidney. Also detected in brain, lung and placenta. {ECO:0000269|PubMed:10498613}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2G59  (X-ray  2.19A  2GJT  (X-ray  2.15A 
DBSNP NA 
Subcellular location [CC]Membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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