| Gene Information | |
|---|---|
| Gene Name | GLDC |
| Organism | Homo sapiens (Human) |
| Gene Length | 1020 |
| Protein Names | Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)) |
| Target Name | glycine dehydrogenase [decarboxylating], mitochondrial |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000178445 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P23378 |
| Gene Card | GLDC |
| Uniprot ID | P23378 |
| Pfam | PF01212; PF02347 |
| In ASD | no |
| Allosteric Prediction | no (-0.008626007) |
| Ortholog in Animals | Alpaca_ GLDC ( ortholog_one2one ) Dog_ GLDC ( ortholog_one2one ) GuineaPig_ GLDC ( ortholog_one2one ) Macaque_ GLDC ( ortholog_one2one ) Mouse_ Gldc ( ortholog_one2one ) Pig_ GLDC ( ortholog_one2one ) Rat_ Gldc ( ortholog_one2one ) Rabbit_ GLDC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | kidney, liver, placenta |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6I33 (X-ray 2.30A ) 6I34 (X-ray 2.10A ) 6I35 (X-ray 2.00A ) |
| DBSNP | rs376578742 rs1554648117 rs386833589 rs386833593 rs10975674 rs150171524 rs774093619 rs761957837 rs121964976 rs121964974 rs772871471 rs1374110692 rs386833556 rs188269735 rs758029533 rs1406713104 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:28244183}. |
| Mouse PG classification | NA |
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