| Gene Information | |
|---|---|
| Gene Name | PDI5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 663 |
| Protein Names | Protein-arginine deiminase type-4 (EC 3.5.3.15) (HL-60 PAD) (Peptidylarginine deiminase IV) (Protein-arginine deiminase type IV) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UM07 |
| Gene Card | PADI4 |
| Uniprot ID | Q9UM07 |
| Pfam | PF03068; PF08527; PF08526 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in eosinophils and neutrophils, not expressed in peripheral monocytes or lymphocytes. {ECO:0000269|PubMed:11435484}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WD8 (X-ray 2.80A ) 1WD9 (X-ray 2.60A ) 1WDA (X-ray 2.30A ) 2DEW (X-ray 2.10A ) 2DEX (X-ray 2.10A ) 2DEY (X-ray 2.25A ) 2DW5 (X-ray 2.30A ) 3APM (X-ray 2.50A ) 3APN (X-ray 2.70A ) 3B1T (X-ray 2.50A ) 3B1U (X-ray 2.10A ) 4DKT (X-ray 2.98A ) 4X8C (X-ray 3.10A ) 4X8G (X-ray 3.29A ) 5N0M (X-ray 2.18A ) 5N0Y (X-ray 2.23A ) 5N0Z (X-ray 2.52A ) 5N1B (X-ray 2.90A ) |
| DBSNP | rs35381732 rs11203366 rs35809521 rs11203367 rs143187209 rs34309058 rs874881 rs12733102 rs11588132 rs35903413 rs1748020 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15629448}. Nucleus {ECO:0000269|PubMed:15629448}. Cytoplasmic granule {ECO:0000269|PubMed:11435484}. Note=Cytoplasmic granules of eosinophils and neutrophils. {ECO:0000269|PubMed:11435484}. |
| Mouse PG classification | NA |
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