Gene Information
Gene NameMBLAC1
OrganismHomo sapiens (Human)
Gene Length266
Protein NamesMetallo-beta-lactamase domain-containing protein 1 (EC 3.1.27.-) (Endoribonuclease MBLAC1)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000214309 )
Evolutionary StageEumetazoa
AlphaFoldDBA4D2B0
Gene CardMBLAC1
Uniprot IDA4D2B0
PfamPF00753
In ASDno
Allosteric Predictionno (-2.253077246)
Ortholog in AnimalsAlpaca_ MBLAC1 ( ortholog_one2one )
Dog_ MBLAC1 ( ortholog_one2one )
GuineaPig_ MBLAC1 ( ortholog_one2one )
Macaque_ MBLAC1 ( ortholog_one2one )
Mouse_ Mblac1 ( ortholog_one2one )
Pig_ MBLAC1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4V0H  (X-ray  1.79A 
DBSNP rs17852945  rs17852946 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:30507380}. Nucleus {ECO:0000269|PubMed:30507380}. Note=Localizes in the nucleus during early S-phase of the cell cycle. {ECO:0000269|PubMed:30507380}.
Mouse PG classificationNA
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