| Gene Information | |
|---|---|
| Gene Name | GK |
| Organism | Homo sapiens (Human) |
| Gene Length | 559 |
| Protein Names | Glycerol kinase (GK) (Glycerokinase) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000198814 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P32189 |
| Gene Card | GK |
| Uniprot ID | P32189 |
| Pfam | PF02782; PF00370 |
| In ASD | no |
| Allosteric Prediction | yes (0.304537145) |
| Ortholog in Animals | Alpaca_ GK ( ortholog_one2many ) Dog_ GK ( ortholog_one2many ) Mouse_ Gk ( ortholog_one2many ) Rat_ Gk ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | GK3P, GK2, GK5, XYLB, SHPK, FGGY |
| Tissue | whole.blood |
| Tissue Specificity | Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17857267 rs17854203 rs132630331 rs132630328 rs132630330 |
| Subcellular location [CC] | Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm. |
| Mouse PG classification | NA |
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