| Gene Information | |
|---|---|
| Gene Name | GJE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 279 |
| Protein Names | Gap junction gamma-3 protein (Connexin-30.2) (Cx30.2) (Connexin-31.3) (Cx31.3) (Gap junction epsilon-1 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000203733 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8NFK1 |
| Gene Card | GJC3 |
| Uniprot ID | Q8NFK1 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-1.439301102) |
| Ortholog in Animals | Alpaca_ GJE1 ( ortholog_one2one ) Dog_ GJE1 ( ortholog_one2one ) GuineaPig_ GJE1 ( ortholog_one2one ) Mouse_ Gje1 ( ortholog_one2one ) Pig_ GJE1 ( ortholog_one2one ) Rat_ Gje1 ( ortholog_one2one ) Rabbit_ GJE1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GJC2, GJC1, GJD4, GJA4, GJA1, GJA8, GJA5, GJA3, GJB3, GJB1, GJB2, GJB5, GJB4, GJB6, GJB7, GJA10, GJA9, GJD2, GJD3, GJC3 |
| Tissue | NA |
| Tissue Specificity | CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney. {ECO:0000269|PubMed:12151525, ECO:0000269|PubMed:12881038}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6L3T (EM 2.34A ) 6L3U (EM 2.53A ) 6L3V (EM 2.63A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |