| Gene Information | |
|---|---|
| Gene Name | GJD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 294 |
| Protein Names | Gap junction delta-3 protein (Connexin-31.9) (Cx31.9) (Gap junction alpha-11 protein) (Gap junction chi-1 protein) |
| Target Name | gap junction delta-3 protein |
| Target Type | Literature-reported target |
| Gene Age | 680 ( ENSG00000183153 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N144 |
| Gene Card | GJD3 |
| Uniprot ID | Q8N144 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-0.715798663) |
| Ortholog in Animals | Alpaca_ GJD3 ( ortholog_one2one ) GuineaPig_ GJD3 ( ortholog_one2one ) Macaque_ GJD3 ( ortholog_one2one ) Mouse_ Gjd3 ( ortholog_one2one ) Rat_ Gjd3 ( ortholog_one2one ) Rabbit_ GJD3 ( ortholog_one2one ) |
| Ohnologs | GJA8 |
| Paralogs | GJD2, GJA10, GJA9, GJC3, GJA4, GJA1, GJA8, GJA5, GJA3, GJB3, GJB1, GJB2, GJB5, GJB4, GJB6, GJB7, GJC2, GJC1, GJD4, GJE1 |
| Tissue | NA |
| Tissue Specificity | Expressed in vascular smooth muscle cells. Found in heart, colon, and artery (at protein level). Found in cerebral cortex, heart, liver, lung, kidney, spleen and testis. {ECO:0000269|PubMed:12154091, ECO:0000269|PubMed:12176752}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12154091}; Multi-pass membrane protein {ECO:0000269|PubMed:12154091}. Cell junction, gap junction {ECO:0000269|PubMed:12154091}. |
| Mouse PG classification | NA |
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