| Gene Information | |
|---|---|
| Gene Name | GJD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 321 |
| Protein Names | Gap junction delta-2 protein (Connexin-36) (Cx36) (Gap junction alpha-9 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000159248 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UKL4 |
| Gene Card | GJD2 |
| Uniprot ID | Q9UKL4 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-0.265643041) |
| Ortholog in Animals | Alpaca_ GJD2 ( ortholog_one2one ) Dog_ GJD2 ( ortholog_one2one ) GuineaPig_ GJD2 ( ortholog_one2one ) Macaque_ GJD2 ( ortholog_one2one ) Mouse_ Gjd2 ( ortholog_one2one ) Pig_ GJD2 ( ortholog_one2one ) Rat_ Gjd2 ( ortholog_one2one ) Rabbit_ GJD2 ( ortholog_one2one ) |
| Ohnologs | GJA1P1 |
| Paralogs | GJD3, GJA10, GJA9, GJC3, GJA4, GJA1, GJA8, GJA5, GJA3, GJB3, GJB1, GJB2, GJB5, GJB4, GJB6, GJB7, GJC2, GJC1, GJD4, GJE1 |
| Tissue | pineal.gland, pituitary.gland |
| Tissue Specificity | Highly expressed in neurons. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2N6A (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Mouse PG classification | NA |
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