| Gene Information | |
|---|---|
| Gene Name | GJC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | Gap junction gamma-1 protein (Connexin-45) (Cx45) (Gap junction alpha-7 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000182963 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P36383 |
| Gene Card | GJC1 |
| Uniprot ID | P36383 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-0.271881245) |
| Ortholog in Animals | Alpaca_ GJC1 ( ortholog_one2one ) Dog_ GJC1 ( ortholog_one2one ) GuineaPig_ GJC1 ( ortholog_one2one ) Macaque_ GJC1 ( ortholog_one2one ) Mouse_ Gjc1 ( ortholog_one2one ) Pig_ GJC1 ( ortholog_one2one ) Rat_ Gjc1 ( ortholog_one2one ) Rabbit_ GJC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GJC2, GJD4, GJE1, GJA4, GJA1, GJA8, GJA5, GJA3, GJB3, GJB1, GJB2, GJB5, GJB4, GJB6, GJB7, GJA10, GJA9, GJD2, GJD3, GJC3 |
| Tissue | substantia.nigra, uterus |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3SHW (X-ray 2.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Mouse PG classification | NA |
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