| Gene Information | |
|---|---|
| Gene Name | GJB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 270 |
| Protein Names | Gap junction beta-3 protein (Connexin-31) (Cx31) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000188910 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75712 |
| Gene Card | GJB3 |
| Uniprot ID | O75712 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-0.742804729) |
| Ortholog in Animals | Dog_ CXNC ( ortholog_one2one ) GuineaPig_ GJB3 ( ortholog_one2one ) Macaque_ GJB3 ( ortholog_one2one ) Mouse_ Gjb3 ( ortholog_one2one ) Pig_ GJB3 ( ortholog_one2one ) Rat_ Gjb3 ( ortholog_one2one ) Rabbit_ GJB3 ( ortholog_one2one ) |
| Ohnologs | GJB6, GJB7, GJB2, GJB1 |
| Paralogs | GJB5, GJB4, GJB7, GJB1, GJB2, GJB6, GJA4, GJA1, GJA8, GJA5, GJA3, GJA10, GJA9, GJD2, GJD3, GJC3, GJC2, GJC1, GJD4, GJE1 |
| Tissue | esophagus, skin, esophagus.mucosa, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs74315316 rs74315315 rs1805063 rs74315321 rs74315317 rs74315320 rs74315318 rs61734064 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Mouse PG classification | NA |
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