| Gene Information | |
|---|---|
| Gene Name | OXGR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | 2-oxoglutarate receptor 1 (Alpha-ketoglutarate receptor 1) (G-protein coupled receptor 80) (G-protein coupled receptor 99) (P2Y purinoceptor 15) (P2Y15) (P2Y-like GPCR) (P2Y-like nucleotide receptor) |
| Target Name | oxoglutarate receptor |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000165621 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96P68 |
| Gene Card | OXGR1 |
| Uniprot ID | Q96P68 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.011851357) |
| Ortholog in Animals | Alpaca_ OXGR1 ( ortholog_one2one ) Dog_ OXGR1 ( ortholog_one2one ) GuineaPig_ OXGR1 ( ortholog_one2one ) Macaque_ OXGR1 ( ortholog_one2one ) Mouse_ Oxgr1 ( ortholog_one2one ) Rat_ Oxgr1 ( ortholog_one2one ) Rabbit_ OXGR1 ( ortholog_one2one ) |
| Ohnologs | P2RY1 |
| Paralogs | FFAR3, GPR42, FFAR2, GPR82, GPR31, FFAR1, HCAR3, HCAR1, HCAR2, OXER1, P2RY2, P2RY4, P2RY1, P2RY6, SUCNR1 |
| Tissue | NA |
| Tissue Specificity | Detected in kidney and, to a lower extent, in placenta. Not detected in brain tissues including the frontal cortex, caudate putamen, thalamus, hypothalamus, hippocampus or pons. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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