| Gene Information | |
|---|---|
| Gene Name | GJA5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | Gap junction alpha-5 protein (Connexin-40) (Cx40) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000265107 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P36382 |
| Gene Card | GJA5 |
| Uniprot ID | P36382 |
| Pfam | PF00029; PF16791 |
| In ASD | no |
| Allosteric Prediction | no (-0.258320237) |
| Ortholog in Animals | Alpaca_ GJA5 ( ortholog_one2one ) Dog_ GJA5 ( ortholog_one2one ) GuineaPig_ GJA5 ( ortholog_one2one ) Macaque_ GJA5 ( ortholog_one2one ) Mouse_ Gja5 ( ortholog_one2one ) Pig_ GJA5 ( ortholog_one2one ) Rat_ Gja5 ( ortholog_one2one ) Rabbit_ GJA5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GJB3, GJB1, GJB2, GJB5, GJB4, GJB6, GJB7, GJA10, GJA9, GJD2, GJD3, GJC3, GJC2, GJC1, GJD4, GJE1, GJA4, GJA1, GJA8, GJA3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs387906613 rs121434558 rs121434557 rs387906614 rs387906615 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Mouse PG classification | HPG |
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