| Gene Information | |
|---|---|
| Gene Name | GJA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 333 |
| Protein Names | Gap junction alpha-4 protein (Connexin-37) (Cx37) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000187513 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P35212 |
| Gene Card | GJA4 |
| Uniprot ID | P35212 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-0.273655641) |
| Ortholog in Animals | Dog_ GJA4 ( ortholog_one2one ) GuineaPig_ GJA4 ( ortholog_one2one ) Macaque_ GJA4 ( ortholog_one2one ) Mouse_ Gja4 ( ortholog_one2one ) Pig_ GJA4 ( ortholog_one2one ) Rat_ Gja4 ( ortholog_one2one ) Rabbit_ GJA4 ( ortholog_one2one ) |
| Ohnologs | GJA3, GJA10, GJA1, GJB2, GJA1P1 |
| Paralogs | GJA1, GJB3, GJB1, GJB2, GJB5, GJB4, GJB6, GJB7, GJA10, GJA9, GJD2, GJD3, GJC3, GJC2, GJC1, GJD4, GJE1, GJA8, GJA5, GJA3 |
| Tissue | NA |
| Tissue Specificity | Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs147128480 rs41266431 rs1764391 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Mouse PG classification | NA |
| click here to return to the previous page | |