| Gene Information | |
|---|---|
| Gene Name | GJA10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 515 |
| Protein Names | Gap junction alpha-9 protein (Connexin-58) (Cx58) (Connexin-59) (Cx59) (Gap junction alpha-10 protein) |
| Target Name | connexin-62 |
| Target Type | Literature-reported target |
| Gene Age | 93 ( ENSG00000135355 ) 3 ( ENSG00000288435 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P57773 |
| Gene Card | GJA9 |
| Uniprot ID | P57773 |
| Pfam | PF00029 |
| In ASD | no |
| Allosteric Prediction | no (-0.267989583) |
| Ortholog in Animals | Alpaca_ GJA10 ( ortholog_one2one ) Dog_ GJA10 ( ortholog_one2one ) GuineaPig_ GJA10 ( ortholog_one2one ) Macaque_ GJA10 ( ortholog_one2one ) Mouse_ Gja10 ( ortholog_one2one ) Pig_ GJA10 ( ortholog_one2one ) Rat_ Gja10 ( ortholog_one2one ) Rabbit_ GJA10 ( ortholog_one2one ) |
| Ohnologs | GJB6, GJA3, GJB1, GJA8, GJA9, GJA1P1, GJA4, GJB5 |
| Paralogs | GJA9, GJC3, GJD2, GJD3, GJA4, GJA1, GJA8, GJA5, GJA3, GJB3, GJB1, GJB2, GJB5, GJB4, GJB6, GJB7, GJC2, GJC1, GJD4, GJE1 |
| Tissue | NA |
| Tissue Specificity | Highly abundant in skeletal muscle. Also detected in testis. {ECO:0000269|PubMed:12881038}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs880303 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}. |
| Mouse PG classification | NA |
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