| Gene Information | |
|---|---|
| Gene Name | GITR |
| Organism | Homo sapiens (Human) |
| Gene Length | 241 |
| Protein Names | Tumor necrosis factor receptor superfamily member 18 (Activation-inducible TNFR family receptor) (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y5U5 |
| Gene Card | TNFRSF18 |
| Uniprot ID | Q9Y5U5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7KHD (X-ray 2.96A ) 7LAW (X-ray 2.75A ) |
| DBSNP | rs11466676 rs11466687 rs11466688 rs11466693 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted. |
| Mouse PG classification | NA |
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