| Gene Information | |
|---|---|
| Gene Name | IDO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 420 |
| Protein Names | Indoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1) |
| Target Name | indoleamine 2,3-dioxygenase 2 |
| Target Type | Patented-recorded target |
| Gene Age | 36 ( ENSG00000188676 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q6ZQW0 |
| Gene Card | IDO2 |
| Uniprot ID | Q6ZQW0 |
| Pfam | PF01231 |
| In ASD | no |
| Allosteric Prediction | no (-1.00029175) |
| Ortholog in Animals | Alpaca_ IDO2 ( ortholog_one2one ) Dog_ IDO2 ( ortholog_one2one ) GuineaPig_ IDO2 ( ortholog_one2one ) Macaque_ IDO2 ( ortholog_one2one ) Mouse_ Ido2 ( ortholog_one2one ) Pig_ IDO2 ( ortholog_one2one ) Rat_ Ido2 ( ortholog_one2one ) Rabbit_ IDO2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | placenta |
| Tissue Specificity | Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%) (PubMed:25691885). {ECO:0000269|PubMed:17671174, ECO:0000303|PubMed:25691885}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10109853 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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