| Gene Information | |
|---|---|
| Gene Name | NR2E1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 385 |
| Protein Names | Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (hTll) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000112333 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y466 |
| Gene Card | NR2E1 |
| Uniprot ID | Q9Y466 |
| Pfam | PF00104; PF00105 |
| In ASD | no |
| Allosteric Prediction | no (-0.059320648) |
| Ortholog in Animals | Alpaca_ NR2E1 ( ortholog_one2one ) Dog_ NR2E1 ( ortholog_one2one ) GuineaPig_ NR2E1 ( ortholog_one2one ) Macaque_ NR2E1 ( ortholog_one2one ) Mouse_ Nr2e1 ( ortholog_one2one ) Pig_ NR2E1 ( ortholog_one2one ) Rat_ Nr2e1 ( ortholog_one2one ) Rabbit_ NR2E1 ( ortholog_one2one ) |
| Ohnologs | NR2F1 |
| Paralogs | RXRB, NR2E3, NR2F2, RXRA, HNF4A, NR2F6, HNF4G, RXRG, NR2C2, NR2C1, NR2F1 |
| Tissue | amygdala, caudate.nucleus, cerebral.cortex, hippocampus, nucleus.accumbens, putamen |
| Tissue Specificity | Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus. {ECO:0000269|PubMed:9628820}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XAJ (X-ray 3.55A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |