Gene Information
Gene NameGIRK4
OrganismHomo sapiens (Human)
Gene Length419
Protein NamesG protein-activated inward rectifier potassium channel 4 (GIRK-4) (Cardiac inward rectifier) (CIR) (Heart KATP channel) (Inward rectifier K(+) channel Kir3.4) (IRK-4) (KATP-1) (Potassium channel, inwardly rectifying subfamily J member 5)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP48544
Gene CardKCNJ5
Uniprot IDP48544
PfamPF01007; PF17655
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityIslets, exocrine pancreas and heart. Expressed in the adrenal cortex, particularly the zona glomerulosa. {ECO:0000269|PubMed:21311022}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs560269341  rs587777437  rs386352319  rs587777438  rs387906778  rs386352318  rs138295501  rs759363415  rs7102584  rs199830292 
Subcellular location [CC]Membrane {ECO:0000269|PubMed:22315453, ECO:0000269|PubMed:24037882};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
click here to return to the previous page