| Gene Information | |
|---|---|
| Gene Name | GIPC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 315 |
| Protein Names | PDZ domain-containing protein GIPC2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000137960 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8TF65 |
| Gene Card | GIPC2 |
| Uniprot ID | Q8TF65 |
| Pfam | PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.721485241) |
| Ortholog in Animals | Alpaca_ GIPC2 ( ortholog_one2one ) Dog_ GIPC2 ( ortholog_one2one ) GuineaPig_ GIPC2 ( ortholog_one2one ) Macaque_ GIPC2 ( ortholog_one2one ) Mouse_ Gipc2 ( ortholog_one2one ) Pig_ GIPC2 ( ortholog_one2one ) Rat_ Gipc2 ( ortholog_one2one ) Rabbit_ GIPC2 ( ortholog_one2one ) |
| Ohnologs | GIPC1, GIPC3 |
| Paralogs | GIPC1, GIPC3 |
| Tissue | adrenal.gland, pancreas, small.intestine.Peyers.patch, spleen |
| Tissue Specificity | Expressed at highest levels in ascending colon and at moderate levels in adult kidney. Expressed at low levels in adult pancreas and at very low levels in adult liver. Expression is down-regulated in several primary tumors, such as kidney, colon and rectal tumors. {ECO:0000269|PubMed:11836570}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3GGE (X-ray 2.60A ) |
| DBSNP | rs17101180 rs540742 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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