Gene Information
Gene NameMPZL2
OrganismHomo sapiens (Human)
Gene Length215
Protein NamesMyelin protein zero-like protein 2 (Epithelial V-like antigen 1)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000149573 )
Evolutionary StageVertebrata
AlphaFoldDBO60487
Gene CardMPZL2
Uniprot IDO60487
PfamPF07686
In ASDno
Allosteric Predictionno (-1.77165954)
Ortholog in AnimalsAlpaca_ MPZL2 ( ortholog_one2one )
Dog_ MPZL2 ( ortholog_one2one )
Macaque_ MPZL2 ( ortholog_one2one )
Mouse_ Mpzl2 ( ortholog_one2one )
Pig_ MPZL2 ( ortholog_one2one )
Rat_ Mpzl2 ( ortholog_one2one )
Rabbit_ MPZL2 ( ortholog_one2one )
OhnologsNA
ParalogsMPZ, MPZL3, MPZL1, JAML, SCN2B, SCN4B
TissueNA
Tissue SpecificityWidely expressed. In fetal tissues, highest expression in the inner ear. In adult tissues, highest levels in thymus and lung. {ECO:0000269|PubMed:29961571}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs187493775 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
click here to return to the previous page