| Gene Information | |
|---|---|
| Gene Name | GIMAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 306 |
| Protein Names | GTPase IMAP family member 1 (Immunity-associated protein 1) (hIMAP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 101 ( ENSG00000213203 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WWP7 |
| Gene Card | GIMAP1 |
| Uniprot ID | Q8WWP7 |
| Pfam | PF04548 |
| In ASD | no |
| Allosteric Prediction | no (-1.277157058) |
| Ortholog in Animals | GuineaPig_ GIMAP1 ( ortholog_one2one ) Mouse_ Gimap1 ( ortholog_one2one ) Rat_ Gimap1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GIMAP6, GIMAP5, GIMAP4, GIMD1, GIMAP2, GIMAP7, GIMAP8 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. Detected in T-cells. {ECO:0000269|PubMed:11814688, ECO:0000269|PubMed:23454188}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3V70 (X-ray 2.21A ) |
| DBSNP | rs7811263 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P70224}; Single-pass type IV membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P70224}; Single-pass type IV membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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