| Gene Information | |
|---|---|
| Gene Name | ETV1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 477 |
| Protein Names | ETS translocation variant 1 (Ets-related protein 81) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000006468 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P50549 |
| Gene Card | ETV1 |
| Uniprot ID | P50549 |
| Pfam | PF00178; PF04621 |
| In ASD | no |
| Allosteric Prediction | yes (0.445567155) |
| Ortholog in Animals | Alpaca_ ETV1 ( ortholog_one2one ) Dog_ ETV1 ( ortholog_one2one ) GuineaPig_ ETV1 ( ortholog_one2one ) Macaque_ ETV1 ( ortholog_one2one ) Mouse_ Etv1 ( ortholog_one2one ) Pig_ ETV1 ( ortholog_one2one ) Rat_ Etv1 ( ortholog_one2one ) Rabbit_ ETV1 ( ortholog_one2one ) |
| Ohnologs | ETV4 |
| Paralogs | ELK1, ETV6, ERG, ERF, ETV4, ETV7, ELF4, ELF3, EHF, ETV2, ETV3L, ETS2, FLI1, GABPA, ETV5, ELF5, ETV3, ELK3, ETS1, ELF2, SPI1, ELK4, ELF1, SPIB, FEV, SPIC, ERFL, SPDEF |
| Tissue | cerebellum, cerebellar.hemisphere |
| Tissue Specificity | Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:7651741}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4AVP (X-ray 1.82A ) 4BNC (X-ray 2.90A ) 5ILS (X-ray 1.40A ) |
| DBSNP | rs9639168 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}. |
| Mouse PG classification | NA |
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