Gene Information
Gene NameKIAA1283
OrganismHomo sapiens (Human)
Gene Length1885
Protein NamesC3 and PZP-like alpha-2-macroglobulin domain-containing protein 8
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8IZJ3
Gene CardCPAMD8
Uniprot IDQ8IZJ3
PfamPF00207; PF07703; PF07677; PF07648; PF12248; PF01835; PF17791; PF17789; PF07678
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine (PubMed:15177561). Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body (PubMed:27839872). {ECO:0000269|PubMed:15177561, ECO:0000269|PubMed:27839872}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs10426545  rs4808551  rs3745340  rs3745335  rs1824152  rs9305083  rs2250918  rs706761  rs1057519340  rs1054533 
Subcellular location [CC]Secreted {ECO:0000305|PubMed:15177561}. Cell membrane {ECO:0000269|PubMed:15177561};
Peripheral membrane protein {ECO:0000269|PubMed:15177561};
Extracellular side {ECO:0000269|PubMed:15177561}.
Mouse PG classificationNA
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