| Gene Information | |
|---|---|
| Gene Name | CMTR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 835 |
| Protein Names | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (EC 2.1.1.57) (Cap methyltransferase 1) (Cap1 2'O-ribose methyltransferase 1) (MTr1) (hMTr1) (FtsJ methyltransferase domain-containing protein 2) (Interferon-stimulated gene 95 kDa protein) (ISG95) |
| Target Name | cap-specific mrna (nucleoside-2'-o-)-methyltransferase 1 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000137200 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N1G2 |
| Gene Card | CMTR1 |
| Uniprot ID | Q8N1G2 |
| Pfam | PF01728; PF01585 |
| In ASD | no |
| Allosteric Prediction | no (-0.841978083) |
| Ortholog in Animals | Alpaca_ CMTR1 ( ortholog_one2one ) Dog_ CMTR1 ( ortholog_one2one ) GuineaPig_ CMTR1 ( ortholog_one2one ) Macaque_ CMTR1 ( ortholog_one2one ) Mouse_ Cmtr1 ( ortholog_one2one ) Pig_ CMTR1 ( ortholog_one2one ) Rat_ Cmtr1 ( ortholog_one2one ) Rabbit_ CMTR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CMTR2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4N48 (X-ray 2.70A ) 4N49 (X-ray 1.90A ) 4N4A (X-ray 2.35A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18533109, ECO:0000269|PubMed:21310715}. |
| Mouse PG classification | NA |
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