| Gene Information | |
|---|---|
| Gene Name | IL17F |
| Organism | Homo sapiens (Human) |
| Gene Length | 163 |
| Protein Names | Interleukin-17F (IL-17F) (Cytokine ML-1) |
| Target Name | cytokine ml-1 |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000112116 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96PD4 |
| Gene Card | IL17F |
| Uniprot ID | Q96PD4 |
| Pfam | PF06083 |
| In ASD | no |
| Allosteric Prediction | no (-0.534199514) |
| Ortholog in Animals | Alpaca_ IL17F ( ortholog_one2one ) GuineaPig_ IL17F ( ortholog_one2one ) Macaque_ IL17F ( ortholog_one2one ) Mouse_ Il17f ( ortholog_one2one ) Pig_ IL17F ( ortholog_one2one ) Rat_ Il17f ( ortholog_one2one ) Rabbit_ IL17F ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IL17D, IL17B, IL17A, IL17C, IL25 |
| Tissue | NA |
| Tissue Specificity | Expressed in T-helper 1 and T-helper 2 cells, basophils and mast cells. {ECO:0000269|PubMed:11591768}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JPY (X-ray 2.85A ) 3JVF (X-ray 3.30A ) 5N92 (X-ray 2.30A ) 5NAN (X-ray 3.30A ) 6HG4 (X-ray 3.32A ) 6HG9 (X-ray 3.62A ) 6HGO (X-ray 2.10A ) 6PPG (X-ray 2.75A ) |
| DBSNP | rs748486078 rs2397084 rs11465553 rs763780 |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:Q7TNI7}. |
| Mouse PG classification | NA |
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